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MEBO is the English abbreviation for Moist Exposed Burn Ointment and is the core pharmaceutical product for implementing Regenerative Medical Technology.

The patented mechanism of MEBO Wound Ointment is based on beeswax and sesame oil. Beeswax provides the frame structure that holds sesame oil droplets containing all active constituents. The core active constituents are β-sitosterol, baicalin, and berberine: β-sitosterol has anti-inflammatory and antioxidant properties; baicalin has anti-microbial, anti-inflammatory, analgesic, nerve-protective, and antioxidant properties; berberine has anti-microbial and anti-inflammatory properties.

• Skin Grafting: Such as conventional split-thickness skin grafting, microskin grafting, MEEK microskin grafting, and skin flap transplantation. MEBO Wound Ointment is applied before surgery for wound debridement and wound bed preparation, and after surgery to promote graft survival and epithelialization.
• Negative Pressure Wound Therapy (NPWT): MEBO Wound Ointment can be used alternately with NPWT.
• Other Topical Agents: MEBO Wound Ointment can be combined with other topical medications, such as antibiotics/antimicrobial agents and growth factors, applied sequentially or alternately according to the wound condition.
• CO2 Laser Therapy: MEBO Wound Ointment is applied immediately after fractional CO2 laser treatment to promote wound healing and reduce scar formation and hyperpigmentation.
• Physical Therapy: In the wound healing stage, MEBO Wound Ointment can be combined with red and/or blue light therapy to further prevent infection and accelerate wound healing.

• Acute Wounds: Dressing change is performed every 4 hours. The medication principles are “early application” (best applied within 4 hours post-injury) and “continuous application” (uninterrupted use throughout the treatment course).
• Chronic Wounds: Dressing change is performed once or twice daily.

• Burn Wounds: First-, second-, and third-degree burns, as well as thermal, chemical, and electrical burns, etc.
• Chronic Wounds: Diabetic foot ulcers (Wagner grades 1–5, including wet, dry, and mixed gangrene); pressure injuries (stages I–IV and unstageable pressure ulcers); lower extremity vascular ulcers; radiation ulcers.
• Surgical Wounds: Post-perianal surgery (perianal abscess, hemorrhoids, anal fistula surgery, etc.); donor sites and recipient sites of skin grafts.
• Traumatic Wounds: Abrasions, lacerations, animal bites, etc.
• Medical Aesthetics: After fractional CO2 laser treatment; post-chemical peeling.
• Special Types of Wounds: Wounds caused by necrotizing fasciitis; wounds with osteonecrosis of bone and joint.

MEBO Wound Ointment is not only suitable for infected wounds but also possesses a clear anti-infective mechanism of action.

Debridement serves as the foundation for anti-infection. The lipophilic components of MEBO Wound Ointment wrap around solid necrotic tissue under the action of body temperature and convert it from a solid to a liquid state through a series of chemical reactions, which are then actively expelled from the wound surface. During this process, bacteria and metabolites are removed together, thereby reducing bacterial colonization and disrupting biofilm structure, creating favorable conditions for anti-infection.

At the same time, MEBO Wound Ointment can also induce morphological changes in bacteria, reducing their reproductive capacity and virulence. Studies have shown that when cultured in a MEBO Wound Ointment-containing medium, the morphology of Escherichia coli and Proteus vulgaris undergoes significant alteration, and bacterial virulence is markedly decreased.